Dr. Bassingthwaighte suggests that propentofylline (Vivitonin, Karsivan) may aid dogs with adverse effects, as it increases NGF. Please see Dr. Bassingwaighte’s article in Dogs Naturally, Librela (Beransa) – Wonder Drug Or Disaster In The Making

Dr. Vince cites recent research suggesting that Lion's Mane can stimulate NGF in the central nervous system, and may also support peripheral nerve regeneration.

Recently Dr. Vince published a Special Report on Librela that is available for FREE on his website . He is planning to provide additional guidance within this on Managing Adverse Reactions. As soon as it becomes available, we will publish it here.

Dr. Rob Silver recommends Lion’s Mane mushroom as it contains terpenes and other molecules that stimulate the production of NGF and a specific NGF found specifically in the central nervous system, called brain-derived NGF or bNGF. Dr. Silver suggests that that using Lion’s Mane concurrently with the use of Librela, or in the event of an adverse side effect, might reduce the development of side-effects or allow the dog (or cat) to overcome those side-effects.